ZORA Publication List
Publications
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2025
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Journal Article
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Sequeira, D. P., Suomalainen, M., Freitag, P. C., Plückthun, A., Klingenbrunner, M., Fischer, L., Hemmi, S., Münz, C., Volle, R., & Greber, U. F. (2025).
Activated blood-derived human primary T cells support replication of HAdV C5 and virus transmission to polarized human primary epithelial cells
Journal of Virology, 99, e0182524. https://doi.org/10.1128/jvi.01825-24
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2023
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Journal Article
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Jetzer, T., Studer, L., Bieri, M., Greber, U., & Hemmi, S. (2023).
Engineered human adenoviruses of species B and C report early, intermediate early and late viral gene expression
Human Gene Therapy, 34, 1230–1247. https://doi.org/10.1089/hum.2023.121
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2022
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Journal Article
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Kannan, A., Suomalainen, M., Volle, R., Bauer, M., Amsler, M., Trinh, H. V., Vavassori, S., Pachlopnik Schmid, J., Vilhena, G., Marin-Gonzalez, A., Pérez, R., Franceschini, A., von Mering, C., Hemmi, S., & Greber, U. F. (2022).
Sequence-Specific Features of Short Double-Strand, Blunt-End RNAs Have RIG-I- and Type 1 Interferon-Dependent or -Independent Anti-Viral Effects
Viruses, 14, 1407. https://doi.org/10.3390/v14071407
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2021
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Journal Article
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Bauer, M., Gomez-Gonzalez, A., Suomalainen, M., Schilling, N., Hemmi, S., & Greber, U. F. (2021).
A viral ubiquitination switch attenuates innate immunity and triggers nuclear import of virion DNA and infection
Science Advances, 7, eabl7150. https://doi.org/10.1126/sciadv.abl7150
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Bieri, M., Hendrickx, R., Bauer, M., Yu, B., Jetzer, T., Dreier, B., Mittl, P. R. E., Sobek, J., Plückthun, A., Greber, U. F., & Hemmi, S. (2021).
The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection
PLoS Pathogens, 17, e1010083. https://doi.org/10.1371/journal.ppat.1010083
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2020
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Journal Article
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Georgi, F., Andriasyan, V., Witte, R., Murer, L., Hemmi, S., Yu, L., Grove, M., Meili, N., Kuttler, F., Yakimovich, A., Turcatti, G., & Greber, U. F. (2020).
The FDA-approved drug Nelfinavir inhibits lytic cell-free, but not cell-associated non-lytic transmission of human adenovirus
Antimicrobial Agents and Chemotherapy, 64, e01002-20. https://doi.org/10.1128/aac.01002-20
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Prasad, V., Suomalainen, M., Jasiqi, Y., Hemmi, S., Hearing, P., Hosie, L., Burgert, H.-G., & Greber, U. F. (2020).
The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections
Nature Communications, 11, 1997. https://doi.org/10.1038/s41467-020-15844-2
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2019
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Journal Article
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Bauer, M., Flatt, J. W., Seiler, D., Cardel, B., Emmenlauer, M., Boucke, K., Suomalainen, M., Hemmi, S., & Greber, U. F. (2019).
The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex
Cell Reports, 29, 3785-3795.e8. https://doi.org/10.1016/j.celrep.2019.11.064
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2018
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Journal Article
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Stichling, N., Suomalainen, M., Flatt, J. W., Schmid, M., Pacesa, M., Hemmi, S., Jungraithmayr, W., Maler, M. D., Freudenberg, M. A., Plückthun, A., May, T., Köster, M., Fejer, G., & Greber, U. F. (2018).
Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor
PLoS Pathogens, 14, e1006914. https://doi.org/10.1371/journal.ppat.1006914
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2017
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Journal Article
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Item, F., Wueest, S., Lemos, V., Stein, S., Lucchini, F. C., Denzler, R., Fisser, M. C., Challa, T. D., Pirinen, E., Kim, Y., Hemmi, S., Gulbins, E., Gross, A., O’Reilly, L. A., Stoffel, M., Auwerx, J., & Konrad, D. (2017).
Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function
Nature Communications, 8, 480. https://doi.org/10.1038/s41467-017-00566-9
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Pacesa, M., Hendrickx, R., Bieri, M., Flatt, J. W., Greber, U. F., & Hemmi, S. (2017).
Small-size recombinant adenoviral hexon protein fragments for the production of virus-type specific antibodies
Virology Journal, 14, 158–171. https://doi.org/10.1186/s12985-017-0822-5
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2016
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Journal Article
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Luisoni, S., Bauer, M., Prasad, V., Boucke, K., Papadopoulos, C., Meyer, H., Hemmi, S., Suomalainen, M., & Greber, U. F. (2016).
Endosomophagy clears disrupted early endosomes but not virus particles during virus entry into cells
Matters, online. https://doi.org/10.19185/matters.201606000013
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Cho, Y.-S., Do, M.-H., Kwon, S.-Y., Moon, C., Kim, K., Lee, K., Lee, S.-J., Hemmi, S., Joo, Y.-E., Kim, M. S., & Jung, C. (2016).
Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers
OncoTarget, 7, 38210–38223. https://doi.org/10.18632/oncotarget.9427
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Raddi, N., Vigant, F., Wagner-Ballon, O., Giraudier, S., Custers, J., Hemmi, S., & Benihoud, K. (2016).
Pseudotyping serotype 5 adenovirus with the fiber from other serotypes uncovers a key role of the fiber protein in adenovirus 5-induced thrombocytopenia
Human Gene Therapy, 27, 193–201. https://doi.org/10.1089/hum.2015.154
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Zafar, S., Parviainen, S., Siurala, M., Hemminki, O., Havunen, R., Tähtinen, S., Bramante, S., Vassilev, L., Wang, H., Lieber, A., Hemmi, S., de Gruijl, T., Kanerva, A., & Hemminki, A. (2016).
Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy
OncoImmunology, 6, e1265717. https://doi.org/10.1080/2162402X.2016.1265717
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2015
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Journal Article
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Cheng, P. F., Shakhova, O., Widmer, D. S., Eichhoff, O. M., Zingg, D., Frommel, S. C., Belloni, B., Raaijmakers, M. I. G., Goldinger, S. M., Santoro, R., Hemmi, S., Sommer, L., Dummer, R., & Levesque, M. P. (2015).
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma
Genome Biology, 16, 42. https://doi.org/10.1186/s13059-015-0594-4
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2014
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Journal Article
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Prasad, V., Suomalainen, M., Pennauer, M., Yakimovich, A., Andriasyan, V., Hemmi, S., & Greber, U. F. (2014).
Chemical induction of unfolded protein response enhances cancer cell killing through lytic virus infection
Journal of Virology, 88, 13086–13098. https://doi.org/10.1128/JVI.02156-14
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2013
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Journal Article
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Trinh, H. V., Grossmann, J., Gehrig, P., Roschitzki, B., Schlapbach, R., Greber, U. F., & Hemmi, S. (2013).
iTRAQ-based and label-free proteomics approaches for studies of human adenovirus infections
International Journal of Proteomics, 2013, 581862. https://doi.org/10.1155/2013/581862
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Widmer, D. S., Hoek, K. S., Cheng, P. F., Eichhoff, O. M., Biedermann, T., Raaijmakers, M. I. G., Hemmi, S., Dummer, R., & Levesque, M. P. (2013).
Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching
Journal of Investigative Dermatology, 133, 2436–2443. https://doi.org/10.1038/jid.2013.115