Publications

ZORA Publication List

Publications

• 2025

  • Journal Article

    • Berger, Simon; Spiri, Silvan; deMello, Andrew; Hajnal, Alex (2025). High-Resolution C. elegans Imaging Across All Larval Stages Journal of Visualized Experiments, 219:e68172.

• 2024

  • Journal Article

    • Hajnal, Alex; Deng, Ting; Lattmann, Evelyn (2024). The role of lin-12 notch in C. elegans anchor cell proliferation Biology Open, 13(12):bio061816.
    • Laranjeira, Ana Cristina; Berger, Simon; Kohlbrenner, Tea; Greter, Nadja R; Hajnal, Alex (2024). Nutritional vitamin B12 regulates RAS/MAPK-mediated cell fate decisions through one-carbon metabolism Nature Communications, 15(1):8178.
    • Kohlbrenner, Tea; Berger, Simon; Laranjeira, Ana Cristina; Aegerter-Wilmsen, Tinri; Comi, Laura Filomena; deMello, Andrew; Hajnal, Alex (2024). Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans PLoS Biology, 22(8):e3002775.

• 2023

  • Journal Article

    • Heinze, Svenia D; Berger, Simon; Engleitner, Stefanie; Daube, Michael; Hajnal, Alex (2023). Prolonging somatic cell proliferation through constitutive hox gene expression in C. elegans Nature Communications, 14(1):6850.

• 2022

  • Journal Article

    • Spiri, Silvan; Berger, Simon; Mereu, Louisa; DeMello, Andrew; Hajnal, Alex (2022). Reciprocal EGFR signaling in the anchor cell ensures precise inter-organ connection during Caenorhabditis elegans vulval morphogenesis Development, 149(1):dev199900.
    • Fergin, Aleksandra; Boesch, Gabriel; Greter, Nadja R; Berger, Simon; Hajnal, Alex (2022). Tissue-specific inhibition of protein sumoylation uncovers diverse SUMO functions during C. elegans vulval development PLoS Genetics, 18(6):e1009978.
    • Lattmann, Evelyn; Deng, Ting; Walser, Michael; Widmer, Patrizia; Rexha-Lambert, Charlotte; Prasad, Vibhu; Eichhoff, Ossia; Daube, Michael; Dummer, Reinhard; Levesque, Mitchell P; Hajnal, Alex (2022). A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans PLoS Biology, 20(2):e3001317.

• 2021

  • Journal Article

    • Berger, Simon; Spiri, Silvan; deMello, Andrew; Hajnal, Alex (2021). Microfluidic-based imaging of complete Caenorhabditis elegans larval development Development, 148(18):online.

• 2020

  • Journal Article

    • Schreier, Verena N; Loehr, Morten O; Deng, Ting; Lattmann, Evelyn; Hajnal, Alex; Neuhauss, Stephan C F; Luedtke, Nathan W (2020). Fluorescent dATP for DNA Synthesis In Vivo ACS Chemical Biology, 15(11):2996-3003.
    • Mereu, Louisa; Morf, Matthias K; Spiri, Silvan; Gutierrez, Peter; Escobar-Restrepo, Juan M; Daube, Michael; Walser, Michael; Hajnal, Alex (2020). Polarized epidermal growth factor secretion ensures robust vulval cell fate specification in Caenorhabditis elegans Development, 147(11):dev175760.
    • Haag, Andrea; Walser, Michael; Henggeler, Adrian; Hajnal, Alex (2020). The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells eLife, 9:e50986.
    • Konietzka, Jan; Fritz, Maximilian; Spiri, Silvan; McWhirter, Rebecca; Leha, Andreas; Palumbos, Sierra; Costa, Wagner Steuer; Oranth, Alexandra; Gottschalk, Alexander; Miller, David M; Hajnal, Alex; Bringmann, Henrik (2020). Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit Current Biology, 30(1):1-16.e13.
    • Deng, Ting; Stempor, Przemyslaw; Appert, Alex; Daube, Michael; Ahringer, Julie; Hajnal, Alex; Lattmann, Evelyn (2020). The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion PLoS Genetics, 16(3):e1008470.
    • Lattmann, Evelyn; Deng, Ting; Hajnal, Alex (2020). To Divide or Invade: A Look Behind the Scenes of the Proliferation-Invasion Interplay in the Caenorhabditis elegans Anchor Cell Frontiers in Cell and Developmental Biology, 8:616051.

• 2019

  • Journal Article

    • Maxeiner, Sabrina; Grolleman, Judith; Schmid, Tobias; Kammenga, Jan; Hajnal, Alex (2019). The hypoxia-response pathway modulates RAS/MAPK-mediated cell fate decisions in Caenorhabditis elegans Life Science Alliance, 2(3):e201800255.

• 2018

  • Journal Article

    • Berger, Simon; Lattmann, Evelyn; Aegerter-Wilmsen, Tinri; Hengartner, Michael; Hajnal, Alex; deMello, Andrew; Casadevall i Solvas, Xavier (2018). Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo Lab on a chip, 18(12):1802.
    • Berger, Simon; Lattmann, Evelyn; Aegerter-Wilmsen, Tinri; Hengartner, Michael; Hajnal, Alex; deMello, Andrew; Casadevall i Solvas, Xavier (2018). Long-term C. elegans immobilization enables high resolution developmental studies in vivo Lab on a chip, 18(9):1359-1368.

• 2017

  • Journal Article

    • Sterken, Mark G; van Bemmelen van der Plaat, Linda; Riksen, Joost A G; Rodriguez, Miriam; Schmid, Tobias; Hajnal, Alex; Kammenga, Jan E; Snoek, Basten L (2017). Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans G3 : Genes, Genomes, Genetics, 7(9):3185-3193.
    • Yang, Qiutan; Roiz, Daniel; Mereu, Louisa; Daube, Michael; Hajnal, Alex (2017). The Invading Anchor Cell Induces Lateral Membrane Constriction during Vulval Lumen Morphogenesis in C. elegans Developmental Cell, 42(3):271-285.e3.
    • Walser, Michael; Umbricht, Christoph Alois; Fröhli, Erika; Nanni, Paolo; Hajnal, Alex (2017). β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans PLoS Genetics, 13(1):e1006592.

• 2016

  • Journal Article

    • Roiz, Daniel; Escobar-Restrepo, Juan Miguel; Leu, Philipp; Hajnal, Alex (2016). The C. elegans hox gene lin-39 controls cell cycle progression during vulval development Developmental Biology, 418(1):124-34.

• 2015

  • Journal Article

    • Hall, Benjamin A; Piterman, Nir; Hajnal, Alex; Fisher, Jasmin (2015). Emergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling Biophysical Journal, 109(2):428-438.
    • Walser, M; Hajnal, A; Escobar-Restrepo, Juan M (2015). FRAP analysis of LET-23::GFP in the vulval epithelial cells of living caenorhabditis elegans larvae Bio-protocol, 5(11):e1489.
    • Thompson, Owen A; Snoek, L Basten; Nijveen, Harm; Sterken, Mark G; Volkers, Rita J M; Brenchley, Rachel; Van't Hof, Arjen; Bevers, Roel P J; Cossins, Andrew R; Yanai, Itai; Hajnal, Alex; Schmid, Tobias; Perkins, Jaryn D; Spencer, David; Kruglyak, Leonid; Andersen, Erik C; Moerman, Donald G; Hillier, LaDeana W; Kammenga, Jan E; Waterston, Robert H (2015). Remarkably divergent regions punctuate the genome assembly of the Caenorhabditis elegans Hawaiian strain CB4856 Genetics, 200(3):975-989.
    • Schmid, Tobias; Hajnal, Alex (2015). Signal transduction during C. elegans vulval development: a NeverEnding story Current Opinion in Genetics & Development, 32:1-9.
    • Schmid, Tobias; Snoek, L Basten; Fröhli, Erika; van der Bent, M Leontien; Kammenga, Jan; Hajnal, Alex (2015). Systemic regulation of RAS/MAPK signaling by the serotonin metabolite 5-HIAA PLoS Genetics, 11(5):e1005236.

• 2014

  • Journal Article

    • Escobar-Restrepo, Juan M; Hajnal, Alex (2014). An intimate look at LET-23 EGFR trafficking in the vulval cells of live C. elegans larvae Worm, 3(3):e965605.
    • Hall, Benjamin A; Jackson, Ethan; Hajnal, Alex; Fisher, Jasmin (2014). Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis Journal of the Royal Society. Interface, 11(98):20140245.
    • Haag, Andrea; Gutierrez, Peter; Bühler, Alessandra; Walser, Michael; Yang, Qiutan; Langouët, Maeva; Kradolfer, David; Fröhli, Erika; Herrmann, Christina J; Hajnal, Alex; Escobar-Restrepo, Juan M (2014). An in vivo EGF receptor localization screen in C. elegans Identifies the Ezrin homolog ERM-1 as a temporal regulator of signaling PLoS Genetics, 10(5):e1004341.
    • van der Bent, M Leontien; Sterken, Mark G; Volkers, Rita J M; Riksen, Joost A G; Schmid, Tobias; Hajnal, Alex; Kammenga, Jan E; Snoek, L Basten (2014). Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans Scientific Reports, 4(4926):online.

• 2013

  • Journal Article

    • Morf, Matthias K; Rimann, Ivo; Alexander, Mariam; Roy, Peter; Hajnal, Alex (2013). The Caenorhabditis elegans homolog of the Opitz syndrome gene, madd-2/Mid1, regulates anchor cell invasion during vulval development Developmental Biology, 374(1):108-114.
    • Snoek, L Basten; Van der Velde, K Joeri; Arends, Danny; Li, Yang; Beyer, Antje; Elvin, Mark; Fisher, Jasmin; Hajnal, Alex; Hengartner, Michael O; Poulin, Gino B; Rodriguez, Miriam; Schmid, Tobias; Schrimpf, Sabine; Xue, Feng; Jansen, Ritsert C; Kammenga, Jan E; Swertz, Morris A (2013). WormQTL-public archive and analysis web portal for natural variation data in Caenorhabditis spp Nucleic Acids Research, 41(D1):D738-D743.

• 2012

  • Journal Article

    • Nusser-Stein, Stefanie; Beyer, Antje; Rimann, Ivo; Adamczyk, Magdalene; Piterman, Nir; Hajnal, Alex; Fisher, Jasmin (2012). Cell-cycle regulation of NOTCH signaling during C. elegans vulval development Molecular Systems Biology, 8:618.
    • Farooqui, Sarfarazhussain; Pellegrino, Mark W; Rimann, Ivo; Morf, Matthias K; Müller, Louisa; Fröhli, Erika; Hajnal, Alex (2012). Coordinated Lumen Contraction and Expansion during Vulval Tube Morphogenesis in Caenorhabditis elegans Developmental Cell, 23(3):494-506.
    • Nakdimon, Itay; Walser, Michael; Fröhli, Erika; Hajnal, Alex (2012). PTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval development PLoS Genetics, 8(8):e1002881.

  • Book Section

    • Beyer, A; Eberhard, R; Piterman, N; Hengartner, M O; Hajnal, A; Fisher, J (2012). A dynamic physical model of cell migration, differentiation and apoptosis in Caenorhabditis elegans In: Goryanin, Igor I; Goryachev, Andrew B . Advances in Systems Biology. New York, NY: Springer, 211-233.

• 2011

  • Journal Article

    • Pellegrino, M W; Farooqui, S; Fröhli, E; Rehrauer, H; Kaeser-Pebernard, S; Müller, F; Gasser, R B; Hajnal, A (2011). LIN-39 and the EGFR/RAS/MAPK pathway regulate C. elegans vulval morphogenesis via the VAB-23 zinc finger protein Development, 138(21):4649-4660.
    • Stetak, A; Hajnal, A (2011). The C. elegans MAGI-1 protein is a novel component of cell junctions that is required for junctional compartmentalization Developmental Biology, 350(1):24-31.
    • Tam, C S; Berthoud, H R; Bueter, Marco; Chakravarthy, M V; Geliebter, A; Hajnal, A; Holst, J; Kaplan, L; Pories, W; Raybould, H; Seeley, R; Strader, A; Ravussin, E (2011). Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium Obesity Reviews, 12(11):984-994.

• 2009

  • Journal Article

    • Pellegrino, M W; Gasser, R B; Sprenger, F; Stetak, A; Hajnal, A (2009). The conserved zinc finger protein VAB-23 is an essential regulator of epidermal morphogenesis in Caenorhabditis elegans Developmental Biology, 336(1):84-93.
    • Stetak, A; Hörndli, F; Maricq, A V; van den Heuvel, S; Hajnal, A (2009). Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans PLoS ONE, 4(6):e6019-e6019.
    • Hoerndli, F J; Walser, M; Fröhli Hoier, E; de Quervain, D; Papassotiropoulos, A; Hajnal, A (2009). A conserved function of c. elegans CASY-1 calsyntenin in associative learning PLoS ONE, 4(3):e4880.

• 2008

  • Journal Article

    • Stetak, A; Gutierrez, P; Hajnal, A (2008). Tissue-specific functions of the Caenorhabditis elegans p120 Ras GTPase activating protein GAP-3 Developmental Biology, 323(2):166-176.

• 2007

  • Journal Article

    • Rimann, I; Hajnal, A (2007). Regulation of anchor cell invasion and uterine cell fates by the egl-43 Evi-1 proto-oncogene in Caenorhabditis elegans.
    • Fisher, J; Piterman, N; Hajnal, A; Henzinger, T A (2007). Predictive modeling of signaling crosstalk during C. elegans vulval development PLoS Computational Biology, 3(5):e92.

• 2006

  • Journal Article

    • Walser, C B; Battu, G; Hoier, E; Hajnal, A (2006). Distinct roles of the Pumilio and FBF translational repressors during C. elegans vulval development Development, 133(17):3461-3471.
    • Stetak, A; Hoier, E; Croce, A; Cassata, G; Di Fiore, P P; Hajnal, A (2006). Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.

• 2005

  • Journal Article

    • Rhiner, C; Gysi, S; Fröhli, E; Hengartner, M O; Hajnal, A (2005). Syndecan regulates cell migration and axon guidance in C. elegans.
    • Zipperlen, P; Nairz, K; Rimann, I; Basler, K; Hafen, E; Hengartner, M; Hajnal, A (2005). A universal method for automated gene mapping Genome Biology, 6(2):R19.

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