Publications

ZORA Publication List

Publications

• 2025

  • Journal Article

    • Berger, S., Spiri, S., deMello, A., & Hajnal, A. (2025). High-Resolution C. elegans Imaging Across All Larval Stages Journal of Visualized Experiments, 219, e68172. https://doi.org/10.3791/68172

• 2024

  • Journal Article

    • Hajnal, A., Deng, T., & Lattmann, E. (2024). The role of lin-12 notch in C. elegans anchor cell proliferation Biology Open, 13, bio061816. https://doi.org/10.1242/bio.061816
    • Laranjeira, A. C., Berger, S., Kohlbrenner, T., Greter, N. R., & Hajnal, A. (2024). Nutritional vitamin B12 regulates RAS/MAPK-mediated cell fate decisions through one-carbon metabolism Nature Communications, 15, 8178. https://doi.org/10.1038/s41467-024-52556-3
    • Kohlbrenner, T., Berger, S., Laranjeira, A. C., Aegerter-Wilmsen, T., Comi, L. F., deMello, A., & Hajnal, A. (2024). Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans PLoS Biology, 22, e3002775. https://doi.org/10.1371/journal.pbio.3002775

• 2023

  • Journal Article

    • Heinze, S. D., Berger, S., Engleitner, S., Daube, M., & Hajnal, A. (2023). Prolonging somatic cell proliferation through constitutive hox gene expression in C. elegans Nature Communications, 14, 6850. https://doi.org/10.1038/s41467-023-42644-1

• 2022

  • Journal Article

    • Spiri, S., Berger, S., Mereu, L., DeMello, A., & Hajnal, A. (2022). Reciprocal EGFR signaling in the anchor cell ensures precise inter-organ connection during Caenorhabditis elegans vulval morphogenesis Development, 149, dev199900. https://doi.org/10.1242/dev.199900
    • Fergin, A., Boesch, G., Greter, N. R., Berger, S., & Hajnal, A. (2022). Tissue-specific inhibition of protein sumoylation uncovers diverse SUMO functions during C. elegans vulval development PLoS Genetics, 18, e1009978. https://doi.org/10.1371/journal.pgen.1009978
    • Lattmann, E., Deng, T., Walser, M., Widmer, P., Rexha-Lambert, C., Prasad, V., Eichhoff, O., Daube, M., Dummer, R., Levesque, M. P., & Hajnal, A. (2022). A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans PLoS Biology, 20, e3001317. https://doi.org/10.1371/journal.pbio.3001317

• 2021

  • Journal Article

    • Berger, S., Spiri, S., deMello, A., & Hajnal, A. (2021). Microfluidic-based imaging of complete Caenorhabditis elegans larval development Development, 148, online. https://doi.org/10.1242/dev.199674

• 2020

  • Journal Article

    • Schreier, V. N., Loehr, M. O., Deng, T., Lattmann, E., Hajnal, A., Neuhauss, S. C. F., & Luedtke, N. W. (2020). Fluorescent dATP for DNA Synthesis In Vivo ACS Chemical Biology, 15, 2996–3003. https://doi.org/10.1021/acschembio.0c00654
    • Mereu, L., Morf, M. K., Spiri, S., Gutierrez, P., Escobar-Restrepo, J. M., Daube, M., Walser, M., & Hajnal, A. (2020). Polarized epidermal growth factor secretion ensures robust vulval cell fate specification in Caenorhabditis elegans Development, 147, dev175760. https://doi.org/10.1242/dev.175760
    • Haag, A., Walser, M., Henggeler, A., & Hajnal, A. (2020). The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells ELife, 9, e50986. https://doi.org/10.7554/eLife.50986
    • Konietzka, J., Fritz, M., Spiri, S., McWhirter, R., Leha, A., Palumbos, S., Costa, W. S., Oranth, A., Gottschalk, A., Miller, D. M., Hajnal, A., & Bringmann, H. (2020). Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit Current Biology, 30, 1-16.e13. https://doi.org/10.1016/j.cub.2019.10.048
    • Deng, T., Stempor, P., Appert, A., Daube, M., Ahringer, J., Hajnal, A., & Lattmann, E. (2020). The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion PLoS Genetics, 16, e1008470. https://doi.org/10.1371/journal.pgen.1008470
    • Lattmann, E., Deng, T., & Hajnal, A. (2020). To Divide or Invade: A Look Behind the Scenes of the Proliferation-Invasion Interplay in the Caenorhabditis elegans Anchor Cell Frontiers in Cell and Developmental Biology, 8, 616051. https://doi.org/10.3389/fcell.2020.616051

• 2019

  • Journal Article

    • Maxeiner, S., Grolleman, J., Schmid, T., Kammenga, J., & Hajnal, A. (2019). The hypoxia-response pathway modulates RAS/MAPK-mediated cell fate decisions in Caenorhabditis elegans Life Science Alliance, 2, e201800255. https://doi.org/10.26508/lsa.201800255

• 2018

  • Journal Article

    • Berger, S., Lattmann, E., Aegerter-Wilmsen, T., Hengartner, M., Hajnal, A., deMello, A., & Casadevall i Solvas, X. (2018). Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo Lab on a Chip, 18, 1802. https://doi.org/10.1039/c8lc90050g
    • Berger, S., Lattmann, E., Aegerter-Wilmsen, T., Hengartner, M., Hajnal, A., deMello, A., & Casadevall i Solvas, X. (2018). Long-term C. elegans immobilization enables high resolution developmental studies in vivo Lab on a Chip, 18, 1359–1368. https://doi.org/10.1039/c7lc01185g

• 2017

  • Journal Article

    • Sterken, M. G., van Bemmelen van der Plaat, L., Riksen, J. A. G., Rodriguez, M., Schmid, T., Hajnal, A., Kammenga, J. E., & Snoek, B. L. (2017). Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans G3 : Genes, Genomes, Genetics, 7, 3185–3193. https://doi.org/10.1534/g3.117.1120
    • Yang, Q., Roiz, D., Mereu, L., Daube, M., & Hajnal, A. (2017). The Invading Anchor Cell Induces Lateral Membrane Constriction during Vulval Lumen Morphogenesis in C. elegans Developmental Cell, 42, 271-285.e3. https://doi.org/10.1016/j.devcel.2017.07.008
    • Walser, M., Umbricht, C. A., Fröhli, E., Nanni, P., & Hajnal, A. (2017). β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans PLoS Genetics, 13, e1006592. https://doi.org/10.1371/journal.pgen.1006592

• 2016

  • Journal Article

    • Roiz, D., Escobar-Restrepo, J. M., Leu, P., & Hajnal, A. (2016). The C. elegans hox gene lin-39 controls cell cycle progression during vulval development Developmental Biology, 418, 124–134. https://doi.org/10.1016/j.ydbio.2016.07.018

• 2015

  • Journal Article

    • Hall, B. A., Piterman, N., Hajnal, A., & Fisher, J. (2015). Emergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling Biophysical Journal, 109, 428–438. https://doi.org/10.1016/j.bpj.2015.06.007
    • Walser, M., Hajnal, A., & Escobar-Restrepo, J. M. (2015). FRAP analysis of LET-23::GFP in the vulval epithelial cells of living caenorhabditis elegans larvae Bio-Protocol, 5, e1489. http://www.bio-protocol.org/e1489
    • Thompson, O. A., Snoek, L. B., Nijveen, H., Sterken, M. G., Volkers, R. J. M., Brenchley, R., Van’t Hof, A., Bevers, R. P. J., Cossins, A. R., Yanai, I., Hajnal, A., Schmid, T., Perkins, J. D., Spencer, D., Kruglyak, L., Andersen, E. C., Moerman, D. G., Hillier, L. W., Kammenga, J. E., & Waterston, R. H. (2015). Remarkably divergent regions punctuate the genome assembly of the Caenorhabditis elegans Hawaiian strain CB4856 Genetics, 200, 975–989. https://doi.org/10.1534/genetics.115.175950
    • Schmid, T., & Hajnal, A. (2015). Signal transduction during C. elegans vulval development: a NeverEnding story Current Opinion in Genetics & Development, 32, 1–9. https://doi.org/10.1016/j.gde.2015.01.006
    • Schmid, T., Snoek, L. B., Fröhli, E., van der Bent, M. L., Kammenga, J., & Hajnal, A. (2015). Systemic regulation of RAS/MAPK signaling by the serotonin metabolite 5-HIAA PLoS Genetics, 11, e1005236. https://doi.org/10.1371/journal.pgen.1005236

• 2014

  • Journal Article

    • Escobar-Restrepo, J. M., & Hajnal, A. (2014). An intimate look at LET-23 EGFR trafficking in the vulval cells of live C. elegans larvae Worm, 3, e965605. https://doi.org/10.4161/21624046.2014.965605
    • Hall, B. A., Jackson, E., Hajnal, A., & Fisher, J. (2014). Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis Journal of the Royal Society Interface, 11, 20140245. https://doi.org/10.1098/rsif.2014.0245
    • Haag, A., Gutierrez, P., Bühler, A., Walser, M., Yang, Q., Langouët, M., Kradolfer, D., Fröhli, E., Herrmann, C. J., Hajnal, A., & Escobar-Restrepo, J. M. (2014). An in vivo EGF receptor localization screen in C. elegans Identifies the Ezrin homolog ERM-1 as a temporal regulator of signaling PLoS Genetics, 10, e1004341. https://doi.org/10.1371/journal.pgen.1004341
    • van der Bent, M. L., Sterken, M. G., Volkers, R. J. M., Riksen, J. A. G., Schmid, T., Hajnal, A., Kammenga, J. E., & Snoek, L. B. (2014). Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans Scientific Reports, 4, online. https://doi.org/10.1038/srep04926

• 2013

  • Journal Article

    • Morf, M. K., Rimann, I., Alexander, M., Roy, P., & Hajnal, A. (2013). The Caenorhabditis elegans homolog of the Opitz syndrome gene, madd-2/Mid1, regulates anchor cell invasion during vulval development Developmental Biology, 374, 108–114. https://doi.org/10.1016/j.ydbio.2012.11.019
    • Snoek, L. B., Van der Velde, K. J., Arends, D., Li, Y., Beyer, A., Elvin, M., Fisher, J., Hajnal, A., Hengartner, M. O., Poulin, G. B., Rodriguez, M., Schmid, T., Schrimpf, S., Xue, F., Jansen, R. C., Kammenga, J. E., & Swertz, M. A. (2013). WormQTL-public archive and analysis web portal for natural variation data in Caenorhabditis spp Nucleic Acids Research, 41, D738–D743. https://doi.org/10.1093/nar/gks1124

• 2012

  • Journal Article

    • Nusser-Stein, S., Beyer, A., Rimann, I., Adamczyk, M., Piterman, N., Hajnal, A., & Fisher, J. (2012). Cell-cycle regulation of NOTCH signaling during C. elegans vulval development Molecular Systems Biology, 8, 618. https://doi.org/10.1038/msb.2012.51
    • Farooqui, S., Pellegrino, M. W., Rimann, I., Morf, M. K., Müller, L., Fröhli, E., & Hajnal, A. (2012). Coordinated Lumen Contraction and Expansion during Vulval Tube Morphogenesis in Caenorhabditis elegans Developmental Cell, 23, 494–506. https://doi.org/10.1016/j.devcel.2012.06.019
    • Nakdimon, I., Walser, M., Fröhli, E., & Hajnal, A. (2012). PTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval development PLoS Genetics, 8, e1002881. https://doi.org/10.1371/journal.pgen.1002881

  • Book Section

    • Beyer, A., Eberhard, R., Piterman, N., Hengartner, M. O., Hajnal, A., & Fisher, J. (2012). A dynamic physical model of cell migration, differentiation and apoptosis in Caenorhabditis elegans In I. I. Goryanin & A. B. Goryachev (Eds.), Advances in Systems Biology (No. 736, Pt 2; Vol. 736, pp. 211–233). Springer. https://doi.org/10.1007/978-1-4419-7210-1_12

• 2011

  • Journal Article

    • Pellegrino, M. W., Farooqui, S., Fröhli, E., Rehrauer, H., Kaeser-Pebernard, S., Müller, F., Gasser, R. B., & Hajnal, A. (2011). LIN-39 and the EGFR/RAS/MAPK pathway regulate C. elegans vulval morphogenesis via the VAB-23 zinc finger protein Development, 138, 4649–4660. https://doi.org/10.1242/dev.071951
    • Tam, C. S., Berthoud, H. R., Bueter, M., Chakravarthy, M. V., Geliebter, A., Hajnal, A., Holst, J., Kaplan, L., Pories, W., Raybould, H., Seeley, R., Strader, A., & Ravussin, E. (2011). Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium Obesity Reviews, 12, 984–994. https://doi.org/10.1111/j.1467-789X.2011.00902.x
    • Stetak, A., & Hajnal, A. (2011). The C. elegans MAGI-1 protein is a novel component of cell junctions that is required for junctional compartmentalization Developmental Biology, 350, 24–31. https://doi.org/10.1016/j.ydbio.2010.10.026

• 2009

  • Journal Article

    • Pellegrino, M. W., Gasser, R. B., Sprenger, F., Stetak, A., & Hajnal, A. (2009). The conserved zinc finger protein VAB-23 is an essential regulator of epidermal morphogenesis in Caenorhabditis elegans Developmental Biology, 336, 84–93. https://doi.org/10.1016/j.ydbio.2009.09.036
    • Stetak, A., Hörndli, F., Maricq, A. V., van den Heuvel, S., & Hajnal, A. (2009). Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans PLoS ONE, 4, e6019–e6019. https://doi.org/10.1371/journal.pone.0006019
    • Hoerndli, F. J., Walser, M., Fröhli Hoier, E., de Quervain, D., Papassotiropoulos, A., & Hajnal, A. (2009). A conserved function of c. elegans CASY-1 calsyntenin in associative learning PLoS ONE, 4, e4880. https://doi.org/10.1371/journal.pone.0004880

• 2008

  • Journal Article

    • Stetak, A., Gutierrez, P., & Hajnal, A. (2008). Tissue-specific functions of the Caenorhabditis elegans p120 Ras GTPase activating protein GAP-3 Developmental Biology, 323, 166–176. https://doi.org/10.1016/j.ydbio.2008.08.026

• 2007

  • Journal Article

    • Rimann, I., & Hajnal, A. (2007). Regulation of anchor cell invasion and uterine cell fates by the egl-43 Evi-1 proto-oncogene in Caenorhabditis elegans. Developmental Biology, 308, 187–195. https://doi.org/10.1016/j.ydbio.2007.05.023
    • Fisher, J., Piterman, N., Hajnal, A., & Henzinger, T. A. (2007). Predictive modeling of signaling crosstalk during C. elegans vulval development PLoS Computational Biology, 3, e92. https://doi.org/10.1371/journal.pcbi.0030092

• 2006

  • Journal Article

    • Stetak, A., Hoier, E., Croce, A., Cassata, G., Di Fiore, P. P., & Hajnal, A. (2006). Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development. The EMBO Journal, 25, 2347–2357. https://doi.org/10.1038/sj.emboj.7601137
    • Walser, C. B., Battu, G., Hoier, E., & Hajnal, A. (2006). Distinct roles of the Pumilio and FBF translational repressors during C. elegans vulval development Development, 133, 3461–3471. https://doi.org/10.1242/dev.02496

• 2005

  • Journal Article

    • Rhiner, C., Gysi, S., Fröhli, E., Hengartner, M. O., & Hajnal, A. (2005). Syndecan regulates cell migration and axon guidance in C. elegans. Development, 132, 4621–4633. https://doi.org/10.1242/dev.02042
    • Canevascini, S., Marti, M., Fröhli, E., & Hajnal, A. (2005). The Caenorhabditis elegans homologue of the proto-oncogene ect-2 positively regulates RAS signalling during vulval development. EMBO Reports, 6, 1169–1175. https://doi.org/10.1038/sj.embor.7400574

Pagination